ATOS vs XXII: Correlation
Measured on weekly returns over the past three years, Atossa Therapeutics, Inc. (ATOS) and 22nd Century Group, Inc (XXII) carry a correlation of 0.38, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ATOS and XXII?
Across a 3-year window, the weekly returns of ATOS and XXII correlate at 0.38, moderate. Recent behaviour matches the longer record: 0.36 over 1 year against 0.38 over 3. Stretching to 5 years gives 0.29, with an annualized covariance of 3348.2 %².
By 3-year correlation, XXII places #8 of the 14 assets tracked against ATOS. Correlation aside, the last 12 months split them widely, with ATOS ahead by 22.6 points (-76.8% versus -99.4%). One caveat on sizing: XXII is 1.6 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ATOS vs XXII: side by side
| ATOS (Atossa Therapeutics, Inc.) | XXII (22nd Century Group, Inc) | |
|---|---|---|
| 1-year return | -76.8% | -99.4% |
| 5-year return | -95.0% | -100.0% |
| Volatility (ann.) | 73.3% | 119.0% |
| Beta vs S&P 500 | 1.97 | 2.06 |
| Max drawdown (3Y) | -94.4% | -100.0% |
| Market cap | – | – |
| P/E (trailing) | – | 0.0 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ATOS | XXII |
|---|---|---|
| 2022 | -66.9% | -70.2% |
| 2023 | +66.0% | -98.7% |
| 2024 | +6.8% | -98.7% |
| 2025 | -37.2% | -99.4% |
| 2026 | -70.2% | -98.7% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ATOS and XXII good diversifiers for each other?
A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between ATOS and XXII?
The ATOS/XXII correlation stands at 0.38 on a 3-year window (1 year: 0.36, 5 years: 0.29), computed from weekly returns as of 2026-08-27.
Is XXII a good diversifier for ATOS?
A fair diversifier. At 0.38, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.38 mean?
A reading of 0.38 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/atos-vs-xxii.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/atos-vs-xxii/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: ATOS correlations · XXII correlations