APVO vs KRYS: Correlation
Measured on weekly returns over the past three years, Aptevo Therapeutics Inc. (APVO) and Krystal Biotech, Inc. (KRYS) carry a correlation of 0.33, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are APVO and KRYS?
On 3 years of weekly data the APVO/KRYS correlation comes out at 0.33, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.20 versus 0.33 over 3 years. The 5-year figure is 0.07, and annualized covariance runs at 2044.1 %².
In APVO's tracked universe of 12 assets, KRYS sits right near the top at #2. Their recent paths diverged sharply: over the last 12 months KRYS outperformed by 234.6 percentage points (-92.5% for APVO against +142.1% for KRYS). Note the risk asymmetry: APVO runs 2.4 times the annualized volatility of the other leg, so equal-weighting the two is not an equal-risk position.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
APVO vs KRYS: side by side
| APVO (Aptevo Therapeutics Inc.) | KRYS (Krystal Biotech, Inc.) | |
|---|---|---|
| 1-year return | -92.5% | +142.1% |
| 5-year return | -100.0% | +523.2% |
| Volatility (ann.) | 121.4% | 50.8% |
| Beta vs S&P 500 | 0.17 | 0.77 |
| Max drawdown (3Y) | -100.0% | -42.3% |
| Market cap | – | $10.6B |
| P/E (trailing) | 0.0 | 44.7 |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | APVO | KRYS |
|---|---|---|
| 2022 | -70.5% | +13.3% |
| 2023 | -92.2% | +56.6% |
| 2024 | -98.5% | +26.3% |
| 2025 | -99.4% | +57.4% |
| 2026 | -74.3% | +45.0% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are APVO and KRYS good diversifiers for each other?
A fair diversifier. At 0.33, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
FAQ
What is the correlation between APVO and KRYS?
The APVO/KRYS correlation stands at 0.33 on a 3-year window (1 year: 0.20, 5 years: 0.07), computed from weekly returns as of 2026-08-27.
Is KRYS a good diversifier for APVO?
A fair diversifier. At 0.33, enough of each asset's movement is its own that the pair has smoothed outcomes historically.
What does a correlation of 0.33 mean?
A reading of 0.33 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/apvo-vs-krys.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/apvo-vs-krys/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: APVO correlations · KRYS correlations
