ANVS vs VXX: Correlation
Annovis Bio, Inc. (ANVS) and iPath Series B S&P 500 VIX Short-Term Futures ETN (VXX) show a negative relationship: their 3-year correlation of weekly returns is -0.25.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ANVS and VXX?
Across a 3-year window, the weekly returns of ANVS and VXX correlate at -0.25, negative, meaning they tend to move in opposite directions. Recent behaviour matches the longer record: -0.16 over 1 year against -0.25 over 3. Stretching to 5 years gives -0.23, with an annualized covariance of -1962.6 %².
VXX is close to the least connected end of ANVS's tracked universe, ranking #9 of 10. Their recent paths diverged sharply: over the last 12 months ANVS outperformed by 26.7 percentage points (-23.0% for ANVS against -49.7% for VXX). One caveat on sizing: ANVS is 2.1 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ANVS vs VXX: side by side
| ANVS (Annovis Bio, Inc.) | VXX (iPath Series B S&P 500 VIX Short-Term Futures ETN) | |
|---|---|---|
| 1-year return | -23.0% | -49.7% |
| 5-year return | -95.0% | -95.6% |
| Volatility (ann.) | 130.1% | 60.9% |
| Beta vs S&P 500 | 2.62 | -3.31 |
| Max drawdown (3Y) | -93.8% | -83.3% |
| Market cap | $0.1B | – |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ANVS | VXX |
|---|---|---|
| 2022 | -23.6% | -23.8% |
| 2023 | +39.2% | -72.5% |
| 2024 | -73.1% | -26.2% |
| 2025 | -31.2% | -42.2% |
| 2026 | -47.7% | -31.6% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ANVS and VXX good diversifiers for each other?
Yes: at -0.25, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between ANVS and VXX?
As of 2026-08-27, the correlation of weekly returns between ANVS and VXX is -0.25 over 3 years, -0.16 over 1 year and -0.23 over 5 years.
Is VXX a good diversifier for ANVS?
Yes: at -0.25, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.25 mean?
On the −1 to +1 scale, -0.25 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/anvs-vs-vxx.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/anvs-vs-vxx/)
Free with attribution; caching and terms are described in the API documentation.
Related comparisons
Hubs: ANVS correlations · VXX correlations
