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AMGN vs VRTX: Correlation

Measured on weekly returns over the past three years, Amgen (AMGN) and Vertex Pharmaceuticals (VRTX) carry a correlation of 0.42, a moderate link.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
0.42
moderate
Correlation (1Y)
0.40
last 12 months
Correlation (5Y)
0.42
long-run
Ann. covariance
331.8
%² · weekly, annualized

How correlated are AMGN and VRTX?

Across a 3-year window, the weekly returns of AMGN and VRTX correlate at 0.42, moderate. Recent behaviour matches the longer record: 0.40 over 1 year against 0.42 over 3. Stretching to 5 years gives 0.42, with an annualized covariance of 331.8 %².

Within AMGN's tracked universe of 31 assets, VRTX comes in at #17 by 3-year correlation. The last year tells two different stories: AMGN led by 15.3 percentage points, +56.0% for AMGN against +40.7% for VRTX. Across three years, the rolling one-year figure varied moderately, from 0.23 to 0.57.

+1.0+0.50-0.5-1.020232026-08-27
One-year correlation, rolled weekly across the last three years.
How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

AMGN vs VRTX: side by side

AMGN (Amgen)VRTX (Vertex Pharmaceuticals)
1-year return+56.0%+40.7%
5-year return+127.8%+174.5%
Volatility (ann.)26.3%30.3%
Beta vs S&P 5000.340.55
Max drawdown (3Y)-22.7%-29.1%
Market cap$236.3B$138.8B
P/E (trailing)27.331.9
Dividend yield2.23%0.00%
Sector / categoryHealth CareHealth Care
Lower P/E: AMGN 27.3 vs 31.9Higher yield: AMGN 2.23% vs 0.00%Smaller drawdown: AMGN -22.7% vs -29.1%Higher 5y return: VRTX +174.5% vs +127.8%
-4%0%+59%2025-09-052026-08-27
Price paths over the last 12 months, both indexed to 100 at the start (weekly closes). AMGN · VRTX

Year-by-year returns

YearAMGNVRTX
2022+20.4%+31.5%
2023+13.5%+40.9%
2024-6.8%-1.0%
2025+29.7%+12.6%
2026+36.2%+20.8%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are AMGN and VRTX good diversifiers for each other?

Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.

FAQ

What is the correlation between AMGN and VRTX?

As of 2026-08-27, the correlation of weekly returns between AMGN and VRTX is 0.42 over 3 years, 0.40 over 1 year and 0.42 over 5 years.

Is VRTX a good diversifier for AMGN?

Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.

What does a correlation of 0.42 mean?

A reading of 0.42 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.

Use this data

JSON API · no key required
$ curl https://www.pairbook.io/api/v1/pairs/amgn-vs-vrtx.json

AMGN vs VRTX: 3-year weekly correlation 0.42AMGN vs VRTX0.42

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Related comparisons

Hubs: AMGN correlations · VRTX correlations