AMGN vs VRTX: Correlation
Measured on weekly returns over the past three years, Amgen (AMGN) and Vertex Pharmaceuticals (VRTX) carry a correlation of 0.42, a moderate link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are AMGN and VRTX?
Across a 3-year window, the weekly returns of AMGN and VRTX correlate at 0.42, moderate. Recent behaviour matches the longer record: 0.40 over 1 year against 0.42 over 3. Stretching to 5 years gives 0.42, with an annualized covariance of 331.8 %².
Within AMGN's tracked universe of 31 assets, VRTX comes in at #17 by 3-year correlation. The last year tells two different stories: AMGN led by 15.3 percentage points, +56.0% for AMGN against +40.7% for VRTX. Across three years, the rolling one-year figure varied moderately, from 0.23 to 0.57.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
AMGN vs VRTX: side by side
| AMGN (Amgen) | VRTX (Vertex Pharmaceuticals) | |
|---|---|---|
| 1-year return | +56.0% | +40.7% |
| 5-year return | +127.8% | +174.5% |
| Volatility (ann.) | 26.3% | 30.3% |
| Beta vs S&P 500 | 0.34 | 0.55 |
| Max drawdown (3Y) | -22.7% | -29.1% |
| Market cap | $236.3B | $138.8B |
| P/E (trailing) | 27.3 | 31.9 |
| Dividend yield | 2.23% | 0.00% |
| Sector / category | Health Care | Health Care |
Year-by-year returns
| Year | AMGN | VRTX |
|---|---|---|
| 2022 | +20.4% | +31.5% |
| 2023 | +13.5% | +40.9% |
| 2024 | -6.8% | -1.0% |
| 2025 | +29.7% | +12.6% |
| 2026 | +36.2% | +20.8% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are AMGN and VRTX good diversifiers for each other?
Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.
FAQ
What is the correlation between AMGN and VRTX?
As of 2026-08-27, the correlation of weekly returns between AMGN and VRTX is 0.42 over 3 years, 0.40 over 1 year and 0.42 over 5 years.
Is VRTX a good diversifier for AMGN?
Yes, to a useful degree: a correlation of 0.42 leaves real independence between the two, which historically damped combined volatility.
What does a correlation of 0.42 mean?
A reading of 0.42 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/amgn-vs-vrtx.json
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[](https://www.pairbook.io/pair/amgn-vs-vrtx/)
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Related comparisons
Hubs: AMGN correlations · VRTX correlations