ALGN vs REPL: Correlation
Measured on weekly returns over the past three years, Align Technology (ALGN) and Replimune Group, Inc. (REPL) carry a correlation of -0.20, a negative link.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ALGN and REPL?
Across a 3-year window, the weekly returns of ALGN and REPL correlate at -0.20, negative, meaning they tend to move in opposite directions. Lately the two have moved closer together, with the 1-year correlation at 0.01 versus -0.20 over 3 years. Stretching to 5 years gives -0.06, with an annualized covariance of -1363.5 %².
Within ALGN's tracked universe of 37 assets, REPL comes in at #29 by 3-year correlation. Correlation aside, the last 12 months split them widely, with REPL ahead by 170.2 points (+11.9% versus +182.1%). One caveat on sizing: REPL is 3.5 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ALGN vs REPL: side by side
| ALGN (Align Technology) | REPL (Replimune Group, Inc.) | |
|---|---|---|
| 1-year return | +11.9% | +182.1% |
| 5-year return | -77.4% | -50.4% |
| Volatility (ann.) | 44.3% | 153.7% |
| Beta vs S&P 500 | 1.51 | 0.48 |
| Max drawdown (3Y) | -66.7% | -92.0% |
| Market cap | $11.3B | $1.5B |
| P/E (trailing) | 27.6 | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | Health Care | US Listed |
Year-by-year returns
| Year | ALGN | REPL |
|---|---|---|
| 2022 | -67.9% | +0.4% |
| 2023 | +29.9% | -69.0% |
| 2024 | -23.9% | +43.7% |
| 2025 | -25.1% | -19.7% |
| 2026 | +1.7% | +60.5% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ALGN and REPL good diversifiers for each other?
Yes: at -0.20, the two have gone their own ways historically, which is what genuine diversification looks like.
FAQ
What is the correlation between ALGN and REPL?
The ALGN/REPL correlation stands at -0.20 on a 3-year window (1 year: 0.01, 5 years: -0.06), computed from weekly returns as of 2026-08-27.
Is REPL a good diversifier for ALGN?
Yes: at -0.20, the two have gone their own ways historically, which is what genuine diversification looks like.
What does a correlation of -0.20 mean?
Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/algn-vs-repl.json
Markdown for the live badge, attribution link included:
[](https://www.pairbook.io/pair/algn-vs-repl/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ALGN correlations · REPL correlations
