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ALGN vs ENGN: Correlation

How closely do Align Technology (ALGN) and enGene Therapeutics Inc. (ENGN) trade together? Their weekly returns over three years give a correlation of -0.22, which is negative.

Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology

Correlation (3Y)
-0.22
negative
Correlation (1Y)
0.22
last 12 months
Correlation (5Y)
-0.16
long-run
Ann. covariance
-1512.0
%² · weekly, annualized

How correlated are ALGN and ENGN?

Over the past 3 years, ALGN and ENGN moved with a correlation of -0.22, which is negative, meaning they tend to move in opposite directions. The past 12 months show a tighter link (0.22) than the 3-year average (-0.22). Over 5 years the correlation is -0.16, and the annualized covariance of weekly returns is -1512.0 %².

Within ALGN's tracked universe of 37 assets, ENGN comes in at #30 by 3-year correlation. Their recent paths diverged sharply: over the last 12 months ALGN outperformed by 67.9 percentage points (+11.9% for ALGN against -56.0% for ENGN). One caveat on sizing: ENGN is 3.5 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.

How is this computed?

Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.

ALGN vs ENGN: side by side

ALGN (Align Technology)ENGN (enGene Therapeutics Inc.)
1-year return+11.9%-56.0%
5-year return-77.4%-80.6%
Volatility (ann.)44.3%156.3%
Beta vs S&P 5001.51-0.97
Max drawdown (3Y)-66.7%-94.9%
Market cap$11.3B$0.1B
P/E (trailing)27.6
Dividend yield0.00%0.00%
Sector / categoryHealth CareUS Listed
Smaller drawdown: ALGN -66.7% vs -94.9%Higher 5y return: ALGN -77.4% vs -80.6%
-71%0%+135%2025-09-052026-08-27
Both assets over the last year, indexed to 100 at the starting week. ALGN · ENGN

Year-by-year returns

YearALGNENGN
2022-67.9%
2023+29.9%-10.6%
2024-23.9%-28.0%
2025-25.1%+35.8%
2026+1.7%-78.8%

Calendar-year price returns; the current year is year-to-date as of the data date above.

Are ALGN and ENGN good diversifiers for each other?

By historical standards, yes. A correlation of -0.22 means the two rarely move for the same reasons.

FAQ

What is the correlation between ALGN and ENGN?

The ALGN/ENGN correlation stands at -0.22 on a 3-year window (1 year: 0.22, 5 years: -0.16), computed from weekly returns as of 2026-08-27.

Is ENGN a good diversifier for ALGN?

By historical standards, yes. A correlation of -0.22 means the two rarely move for the same reasons.

What does a correlation of -0.22 mean?

Correlation ranges from −1 to +1. Values near +1 mean two assets move together, near 0 that they move independently, and negative values that they tend to move in opposite directions. It measures co-movement, not performance.

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ALGN vs ENGN: 3-year weekly correlation -0.22ALGN vs ENGN-0.22

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Hubs: ALGN correlations · ENGN correlations