ALEC vs DNLI: Correlation
Alector, Inc. (ALEC) and Denali Therapeutics Inc. (DNLI) show a moderate relationship: their 3-year correlation of weekly returns is 0.50.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ALEC and DNLI?
On 3 years of weekly data the ALEC/DNLI correlation comes out at 0.50, moderate. Lately the two have drifted apart, with the 1-year correlation at 0.29 versus 0.50 over 3 years. The 5-year figure is 0.51, and annualized covariance runs at 2723.0 %².
Few assets follow ALEC as closely as DNLI, which ranks #3 of 11 tracked partners. Their recent paths diverged sharply: over the last 12 months DNLI outperformed by 58.5 percentage points (-0.4% for ALEC against +58.1% for DNLI).
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ALEC vs DNLI: side by side
| ALEC (Alector, Inc.) | DNLI (Denali Therapeutics Inc.) | |
|---|---|---|
| 1-year return | -0.4% | +58.1% |
| 5-year return | -90.9% | -53.4% |
| Volatility (ann.) | 90.5% | 60.6% |
| Beta vs S&P 500 | 2.06 | 2.02 |
| Max drawdown (3Y) | -89.2% | -63.7% |
| Market cap | $0.3B | $3.9B |
| P/E (trailing) | – | – |
| Dividend yield | 0.00% | 0.00% |
| Sector / category | US Listed | US Listed |
Year-by-year returns
| Year | ALEC | DNLI |
|---|---|---|
| 2022 | -55.3% | -37.6% |
| 2023 | -13.5% | -22.8% |
| 2024 | -76.3% | -5.0% |
| 2025 | -17.5% | -19.0% |
| 2026 | +53.2% | +49.4% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ALEC and DNLI good diversifiers for each other?
Somewhat, no more. With 0.50 correlation, most large moves hit both names, and the diversification benefit stays modest.
FAQ
What is the correlation between ALEC and DNLI?
As of 2026-08-27, the correlation of weekly returns between ALEC and DNLI is 0.50 over 3 years, 0.29 over 1 year and 0.51 over 5 years.
Is DNLI a good diversifier for ALEC?
Somewhat, no more. With 0.50 correlation, most large moves hit both names, and the diversification benefit stays modest.
What does a correlation of 0.50 mean?
On the −1 to +1 scale, 0.50 describes how much the two returns move together: +1 is lockstep, 0 is independence, negative values mean opposite directions. It says nothing about which performed better.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/alec-vs-dnli.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/alec-vs-dnli/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ALEC correlations · DNLI correlations
