ACWI vs GLSI: Correlation
iShares MSCI ACWI ETF (ACWI) and Greenwich LifeSciences, Inc. (GLSI) show a moderate relationship: their 3-year correlation of weekly returns is 0.36.
Data as of 2026-08-27 · refreshed every trading day · weekly returns · methodology
How correlated are ACWI and GLSI?
Across a 3-year window, the weekly returns of ACWI and GLSI correlate at 0.36, moderate. The relationship has been stable: the 1-year correlation (0.34) sits close to the 3-year figure. Stretching to 5 years gives 0.37, with an annualized covariance of 358.2 %².
By 3-year correlation, GLSI places #107 of the 119 assets tracked against ACWI. Correlation aside, the last 12 months split them widely, with GLSI ahead by 37.8 points (+22.7% versus +60.5%). One caveat on sizing: GLSI is 5.3 times as volatile as the other leg, so an equal-dollar split is far from equal-risk.
How is this computed?
Pearson correlation on weekly returns: ρ(A,B) = cov(rA, rB) / (σA · σB), over windows of 52, 156 and 260 weeks. Covariance is annualized (×52) and expressed in %². Full definitions on the methodology page.
ACWI vs GLSI: side by side
| ACWI (iShares MSCI ACWI ETF) | GLSI (Greenwich LifeSciences, Inc.) | |
|---|---|---|
| 1-year return | +22.7% | +60.5% |
| 5-year return | +69.0% | -52.7% |
| Volatility (ann.) | 13.8% | 73.1% |
| Beta vs S&P 500 | 0.92 | 1.76 |
| Max drawdown (3Y) | -16.5% | -61.9% |
| Market cap | – | $0.3B |
| P/E (trailing) | – | – |
| Dividend yield | 1.44% | 0.00% |
| Expense ratio | 0.32% | – |
| Assets under management | $32.5B | – |
| Sector / category | ETF · Global | US Listed |
ACWI, iShares's Global Large-Stock Blend fund, carries $32.5B under management, 1590 holdings, a 0.32% expense ratio, a 1.44% trailing dividend yield.
Year-by-year returns
| Year | ACWI | GLSI |
|---|---|---|
| 2022 | -18.4% | -37.5% |
| 2023 | +22.3% | -30.8% |
| 2024 | +17.4% | +6.7% |
| 2025 | +22.4% | +87.1% |
| 2026 | +14.9% | -10.9% |
Calendar-year price returns; the current year is year-to-date as of the data date above.
Are ACWI and GLSI good diversifiers for each other?
Reasonably. At 0.36, ACWI and GLSI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
FAQ
What is the correlation between ACWI and GLSI?
As of 2026-08-27, the correlation of weekly returns between ACWI and GLSI is 0.36 over 3 years, 0.34 over 1 year and 0.37 over 5 years.
Is GLSI a good diversifier for ACWI?
Reasonably. At 0.36, ACWI and GLSI keep a meaningful degree of independence, and combining them has historically reduced portfolio volatility.
What does a correlation of 0.36 mean?
A reading of 0.36 sits on a scale from −1 (opposite moves) through 0 (unrelated) to +1 (identical moves). Correlation captures direction, not magnitude or performance.
Use this data
$ curl https://www.pairbook.io/api/v1/pairs/acwi-vs-glsi.json
Drop this badge in a README or notebook; it updates with the data:
[](https://www.pairbook.io/pair/acwi-vs-glsi/)
The core API is free. Terms and every endpoint in the API documentation.
Related comparisons
Hubs: ACWI correlations · GLSI correlations
